Thesis Taisha DONNELLY

Auditory verbal hallucinations characterise a large proportion of patients with schizophrenia. Their origin is thought to be due to a failure of internal language, and more specifically of its predictive control, leading to a loss of agentivity. The dysfunction, which disrupts the activity of the language connectome, is thought to involve the left inferior frontal gyrus. The overall aim of this thesis project is, on the one hand, to provide a better description of the neural dynamics of auditory verbal hallucinations and, on the other, to envisage a neurofeedback treatment based on these neural dynamics and on previous research carried out on healthy participants. In the first phase of this thesis, before looking at hallucinations, we are assessing the neural dynamics and brain correlates of language, and more specifically of internal language (endophasia) in healthy adults, using neurophysiological methods (sEEG and MEG).

Supervisor :
Monica BACIU Monica.Baciuuniv-grenoble-alpes.fr (Monica[dot]Baciu[at]univ-grenoble-alpes[dot]fr), Directrice de thèse

Keywords : language, inner speech, connectomics, language, neurocognition, neurophysiology, sEEG, MEG, hallucinations